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欧盟评估非转基因解淀粉芽孢杆菌菌株LMG-S 32676生产的α-淀粉酶的安全性

放大字体  缩小字体 发布日期:2023-10-12  来源:食品伙伴网  作者:泽夕  浏览次数:112
核心提示:2023年10月11日,欧盟食品安全局就一种α-淀粉酶(α-amylase)的安全性评价发布意见。
   食品伙伴网讯  2023年10月11日,欧盟食品安全局就一种α-淀粉酶(α-amylase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因解淀粉芽孢杆菌菌株LMG-S 32676生产的,旨在用于六种食品制造过程:烘焙过程、酿造过程、蒸馏酒精生产、生产葡萄糖浆和其他淀粉水解产物的淀粉加工、精制糖和未精制糖生产以及酵母加工。
 
  经过评估,专家小组认为,在预期的使用条件下(蒸馏酒精生产除外),不能排除饮食暴露引起过敏反应的风险,但这种可能性被认为很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified microorganism Bacillus amyloliquefaciens strain LMG-S 32676 by Enmex SA de CV, a Kerry Company. The food enzyme under assessment is intended to be used in six food manufacturing processes: baking processes, brewing processes, distilled alcohol production, starch processing for the production of glucose syrups and other starch hydrolysates, refined and unrefined sugar production and yeast processing. Since residual amounts of total organic solids (TOS) are removed in distilled alcohol production and starch processing for glucose syrups production and other starch hydrolysates, the dietary exposure estimation was made only for the remaining four food processes. It was estimated to be up to 2.998 mg TOS/kg body weight per day in European populations. The production strain meets the requirements for the QPS approach. As no concerns arising from the manufacturing process were identified, the Panel considered that toxicological tests were not needed for the assessment of this food enzyme. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and two matches with respiratory allergens were found. The Panel considered that a risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded (except for distilled alcohol production), but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
 
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